dogear

enter for all results · esc to close

sci-Plex

ncbi.nlm.nih.govsite

Single-cell chemical perturbation screen of ~650,000 transcriptomes across three cancer cell lines, 188 compounds, and four doses.

from
Computational Biology
added
2026-10-10
likes
0

similar

  1. scPerturb github.com

    Curated and continuously updated single-cell perturbation data resource spanning CRISPR and drug perturbation studies.

  2. MIX-Seq nature.com

    Multiplexed single-cell transcriptional profiling of chemical and genetic perturbation responses across pools of cancer cell lines.

  3. PRISM depmap.org

    Cancer drug sensitivity profiling of >4,500 drugs across >900 cancer cell lines using pooled-cell-line barcoding.

  4. Dixit et al. 2016 Perturb-seq ncbi.nlm.nih.gov

    Pooled CRISPR knockout with single-cell RNA-seq across K562 and dendritic-cell screens, including stimulated conditions and combinatorial perturbations.

  5. Cancer Therapeutics Response Portal (CTRP) portals.broadinstitute.org

    Drug sensitivity profiles across ~900 cancer cell lines for >400 compounds.

  6. LINCS L1000 lincsproject.org

    Gene expression profiles (978 landmark genes) for >20,000 chemical and genetic perturbations across cell lines.

Computational Biology › Benchmarks & Datasets > Drug Response & Perturbation: “Single-cell chemical perturbation screen of ~650,000 transcriptomes across three cancer cell lines, 188 compounds, and four doses.”