scPerturb
Curated and continuously updated single-cell perturbation data resource spanning CRISPR and drug perturbation studies.
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- Computational Biology
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- 2026-10-10
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Norman et al. 2019 CRISPRa Perturb-seq figshare.com
Large-scale CRISPR activation Perturb-seq in K562 cells spanning single-gene and combinatorial perturbations.
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Dixit et al. 2016 Perturb-seq ncbi.nlm.nih.gov
Pooled CRISPR knockout with single-cell RNA-seq across K562 and dendritic-cell screens, including stimulated conditions and combinatorial perturbations.
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Adamson et al. 2016 Perturb-seq ncbi.nlm.nih.gov
CRISPRi Perturb-seq in K562 cells for systematic dissection of the unfolded protein response.
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Replogle et al. 2022 K562 Genome-wide Perturb-seq plus.figshare.com
Genome-scale CRISPRi Perturb-seq targeting nearly all expressed genes in K562 cells.
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Chem-PerturBridge github.com
Harmonized compendium and processing pipelines for small-molecule perturbation transcriptomics across heterogeneous assays and gene panels.
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sci-Plex ncbi.nlm.nih.gov
Single-cell chemical perturbation screen of ~650,000 transcriptomes across three cancer cell lines, 188 compounds, and four doses.
Computational Biology › Benchmarks & Datasets > Drug Response & Perturbation: “Curated and continuously updated single-cell perturbation data resource spanning CRISPR and drug perturbation studies.”