A high-level programming language for generative protein design
2022. [All Versions]. Combining a basic set of building blocks into more complex forms is a universal design principle. Most protein designs have proceeded from a manual bottom-up approach using parts created by nature, but top-down design of proteins is fundamentally hard due…
- from
- AGI & CoCoSci
- added
- 2026-10-10
- likes
- 0
similar
-
A Logic Programming Language for Computational Nucleic Acid Devices pubs.acs.org
ACS Synthetic Biology, 2018. [All Versions]. This paper presents a logic programming language that allows a broad range of computational nucleic acid systems to be designed and analyzed. The language extends standard logic programming with a novel equational theory to express…
-
Universal chemical programming language for robotic synthesis repeatability nature.com
Nature Synthesis, 2024. [All Versions]. [Preprint]. The amount of chemical synthesis literature is growing quickly; however, it takes a long time to share and evaluate new processes among laboratories. This paper presents an approach that uses a universal chemical programming…
-
Design of metalloproteins and novel protein folds using variational autoencoders nature.com
Scientific Reports, 2018. [All Versions]. The design of novel proteins has many applications but remains an attritional process with success in isolated cases. Meanwhile, deep learning technologies have exploded in popularity in recent years and are increasingly applicable to…
-
Evolution-inspired engineering of nonribosomal peptide synthetases science.org
Science, 2024. [All Versions]. Many clinically used drugs are derived from natural microbial products that are assembled in a stepwise fashion by the condensation of amino acids or acyl groups. Using insights from evolutionary analysis, two independent groups now show that the…
-
ProGen2 github.com
Protein language model trained on diverse protein families for sequence generation and fitness prediction.
-
Genetic circuit design automation with Cello 2.0 nature.com
Nature Protocol, 2022. [All Versions]. [Preprint]. Cells interact with their environment, communicate among themselves, track time and make decisions through functions controlled by natural regulatory genetic circuits consisting of interacting biological components. Synthetic…
AGI & CoCoSci › Papers > Domain Specific Language > Declarative DSL Applications: “2022. [All Versions]. Combining a basic set of building blocks into more complex forms is a universal design principle. Most protein designs have proceeded from a manual bottom-up approach using parts created by nature, but top-down design of proteins is fundamentally hard due…”