CpGPT
DNA methylation foundation model pretrained on >150K samples for zero-shot imputation, array conversion, reference mapping, and downstream phenotype prediction.
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- Computational Biology
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- 2026-10-10
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MethylGPT github.com
Transformer foundation model for DNA methylation pretrained on >150K human methylomes across thousands of datasets, with 3M/7M/15M parameter variants.
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scDNAm-GPT github.com
Foundation model for single-cell whole-genome bisulfite sequencing with whole-genome context modeling at single-CpG resolution.
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GeneCompass github.com
Large-scale foundation model integrating DNA regulatory sequences and single-cell transcriptomics from 120M+ cells across multiple species for gene regulation prediction.
Computational Biology › Machine Learning Tasks and Models > Foundation Models > Other Omics Foundation Models: “DNA methylation foundation model pretrained on >150K samples for zero-shot imputation, array conversion, reference mapping, and downstream phenotype prediction.”